Millions of people throughout the world are affected by diabetes mellitus, which is defined by chronic hyperglycemia owing to insulin shortage or resistance. It is anticipated that the prevalence of diabetes mellitus would considerably increase. Diabetes type 2, which is the most common form of this disorder, is linked to a wide range of systemic issues, some of which are connected with dental health. As a result of diabetes, periodontal disorders, xerostomia, candidiasis, and the risk of tooth loss are all made worse, and the relationship between diabetes and oral health is particularly complex. In addition to being more common among diabetics, periodontitis, a severe form of gum disease, also plays a role in the deterioration of glycemic control, so establishing a link that serves in both directions. Moreover, the disease is further complicated by the presence of other oral signs, such as dry mouth, taste problems, and burning mouth syndrome. An in-depth medical history, consistent monitoring of blood glucose levels, and particular considerations during dental operations are all necessary for effective management of oral health in diabetic patients. These measures are used to reduce the likelihood of hypoglycemia and infections. The effects of diabetes on dental health are discussed in this chapter, along with the problems, treatment options, and preventative actions that may be taken to enhance patient outcomes that are associated with diabetes.