Odontogenic maxillary sinusitis is predisposed by odontogenic infections of maxillary posterior dentition. The microbial flora, pathophysiology, radiographic features of odontogenic maxillary sinusitis are different from that of sinusitis caused due to respiratory tract infections. In this disease, patient may remain asymptomatic, and is most commonly incidentally discovered during routine dental radiographic examination. Unliateral sinusitis associated with dental foci of infection is a classic feature of this disease. Computed tomography and cone beam computed tomography helps in delineation and diagnosis of the pathology. Initially, the dental foci of infection should be managed appropriately by the dentist. Depending on the degree of infection and inflammation medical management or surgical management is planned by the otorhinolaryngologist. The medical management involves prescription of anti-biotics and anti-inflammatory drugs. Advanced surgical techniques like functional endoscopic sinus surgery and modified endoscopic sinus surgery are performed to remove the diseased mucosa. Thus, an interdisplinary approach is required for effective management of the maxillary sinus disease. This article uncovers the interlink between dental infections of maxillary posterior teeth and maxillary sinus disease.