Trade across borders benefits companies as well as the countries to which they belong. Increased economic activity as a result of international trade along with the jobs that accompany them can be advantageous to a country. Furthermore, the businesses may grow and become more profitable and it might benefit from the worldwide market when the domestic one is less profitable. Thus, the chapter's goal is to highlight the principal trading blocs in international trade, which is a crucial area to concentrate on to achieve long-term financial success. The Association of Southeast Asian Nations, North American Free Trade Agreement, South Asian Association for Regional Cooperation, and European Union are the major trading blocs of international business which is briefly addressed.