Due to their ubiquitous presence across different matrices of the ecosystem, PPCP has become a topic of global concern. It comprises of many sub-group of chemicals such as pharmaceuticals, antibiotics, soaps, disinfectants, fragrances that we use in our day to day life. These chemicals get discharged into aquatic bodies through waste water effluents, into soil and air and eventually get bio accumulated and biomagnified, thus impacting the overall ecosystem health. The aquatic ecosystem is most prominently impacted by these chemicals that we use on day to day basis to enhance our lifestyle. The aquatic fauna get constantly exposed to the cocktails of PPCP along with other organic ubiquitous pollutants such as micro plastics. Several researches have thrown the light on physiological disruption and endocrine and reproductive dysfunction caused by PPCPs to aquatic organisms. However, the deadly consequences of such ubiquitous exposure with different combination of pollutants are still not properly known. Another major risk that is associated with PPCP is the continuous loading of antibiotics into aquatic bodies through waste effluents as it is increasing the risk of development of antibiotic resistance and superbug formation; imposing great threat to human health. Besides uptake and bioaccumulation PPCPs by some leafy vegetables cultivated in reclaimed water, reported so far could be indicative of the fact that consumption of plants may be another route through which PPCP bioaccumulation and bio magnification occurs in ecosystem.