Advances in Engineering and Sciences (Volume - 1), edited by Prof. K. Viswak Sena Reddy and Dr. Rajesh Reddy Duvvuru, brings together five well-researched chapters highlighting modern applications of artificial intelligence, optimization techniques, and custom power solutions in electrical engineering. The volume addresses congestion management in deregulated power systems using FACTS devices, hydrothermal scheduling through genetic algorithms, power system stabilizer design via AI tools, ATC estimation using machine learning indices, and multi-omics data analysis with machine learning for cancer diagnostics. Bridging core electrical engineering with emerging domains like bioinformatics and smart grid systems, the book delivers both theoretical frameworks and experimental validations. Designed for students, engineers, and interdisciplinary researchers, this volume provides valuable insights into real-time energy optimization, power system reliability, and intelligent control systems.