The phytonutrients plant origin are what give them their therapeutic qualities. The most important sources for treating damaging diseases are these phytochemicals. Numerous phytochemicals have a wide range of functions that assist to strengthen the immune system and provide resistance to chronic illness, thereby defending the body against harmful infections. The comparison has made between traditional medicine drug delivery system and modern novel drug delivery system in this novel trends medicinal plants have contributed more emphasis for therapeutic property. The active constituents can be incorporated in various forms like green synthesis (Herbal nanoparticles), phytosomes, ethosomes, liposomes and many more. The exploration of phytochemicals has been greatly enhanced by the creation of sophisticated instruments for qualitative and quantitative evaluation. However, empirical information on the biological characteristics of numerous plant species has been confirmed. Diverse plant raw extracts and their active ingredients, together with their modes of action, have also been studied for their potential health advantages for people. Natural products, also known as specialised (or secondary) metabolites, are produced in enormous quantities by plants and are a valuable source for modern pharmacy.