The sustainability and environmental friendliness of nanotechnology are increased by using microorganisms concurrently with the biofabrication of nanoparticles. Silver nanoparticles have attracted a lot of attention because their distinctive characteristics. As a result, microbial cells or enzyme, protein, and other biomolecule components are used in either an intracellular or extracellular route to synthesise silver nanoparticles from both prokaryotes and eukaryotes, including bacteria, fungi and yeast. Silver nanoparticles have antibacterial qualities; however the characteristics of nanoparticles (NPs) vary on their size and form, making them unique for different applications. However, by adjusting the reaction conditions throughout the optimisation phase of microbes-mediated synthesis, the desired size and shape of NPs can be achieved. As a result, the synthesis of silver nanoparticles through the use of microbes has lately advanced quickly, and microorganisms are now preferred over chemical and physical methods because they are safer, more eco-friendly, non-toxic, and biocompatible. Because silver nanoparticles are more efficient than their bulk counterparts, they have been investigated for a variety of potential applications, including the livestock sector. Notably, silver nanoparticles have become promising antibacterial agents with the rise of multi-drug resistance pathogens.