A shift from ‘agriculture’ to ‘agribusinesses is being viewed as an essential pathway to revitalize Indian agriculture. While the share of pure agriculture sector in GDP may decline, the share of agribusiness will not and is bound to go up with the demand for value addition continuously increasing. It is in this context that it has long been argued for redefining agriculture as ‘the science and practice of activities relating to production, marketing, distribution, processing and trade of food, feed and fibre (Acharya, 2006). This chapter throws light on major’s challenges in Agriculture in India, Need for Agribusiness Mode, New Opportunities in Agribusiness and Top 10 Farming Business Ideas in India.