Soil enzymes play a key role within the energy transfer through decomposition of soil organic matter and nutrient recycling, and therefore play a very important role in agriculture. These enzymes turn several import antreactions necessary for the life processes of soil microorganisms and additionally facilitate in stabilization of soil structure. Though microorganisms are the origin of soil enzymes, plants and animals additionally contribute to the soil catalyst pool. Soil enzymes respond quickly to any changes in soil management practices and environmental conditions. Their activities are closely associated with physio-chemical and biological properties of the soil. Hence, soil enzymes are used as sensors for soil microbial activity, for soil physio-chemical conditions, and for the influence of soil treatments or climatical factors on soil fertility. Understanding the attainable roles of various soil enzymes in maintaining soil health will facilitate within the soil health and fertility management, notably in agricultural ecosystems. during this entry, we have a tendency to describe the major soil enzymes and their role in nutrient mobilization, soil fertility, and yield property. The results of cropping systems, crop management, and nutrient management practices on soil catalyst activities are discussed. We have a tendency to more discuss the reports on the impact of climatical factors like elevated carbonic acid gas, temperature, and drought on soil enzymes activities. Advancements in catalyst activity assay tools are discussed, followed by prospects within the field of soil enzymes. To conclude, soil enzyme catalyst activity could be a useful tool for assessing and managing productivity of a system.