Despite the increasing energy demand, a significant quantity of crude oil is still present in the reservoir following primary and secondary recovery techniques. To recover more oil, different Enhance Oil Recovery (EOR) methods have been developed. Chemical flooding is one of the EOR methods that can reduce Residual Oil Saturation (ROS) by altering the rock wettability, oil-water Interfacial Tension (IFT), the viscosity of oil, the viscosity of displacing phase fluid, etc. Surfactant Flooding is one of the Chemical EOR (CEOR) techniques, that can improve the recovery of oil by reducing the oil-water IFT, altering the rock wettability to a more water-wet state, and improving the Microscopic Displacement Efficiency. However, the surfactants used are sensitive to the harsh environment characterizing the local reservoirs. The current study aimed at investigating the application of Ionic Liquids (ILs), as an alternative to conventional surfactants in enhanced oil recovery process in a part of the Upper Assam Basin, India. ILs are purely ionic materials with melting points lower than 100 oC. In contrast to traditional solvents, which are composed of molecules, ILs are formed by ions, which are recognized as typical salts with good solubility, thermal stability, and effective surface activity. They are also known as environment friendly. ILs can improve the oil recovery by lowering the oil-water IFT and controlling the Clay Swelling in sandstone reservoirs. The petrographic analysis of the rock of the study area reveals the presence of smectite clay minerals which can swell in the low salinity environment and reduce the permeability. Other clay minerals present in the reservoir rock of the study area are kaolinite and illite which can also damage the formation by clay migration and swelling-induced migration. The study shows that the ILs can be a good alternative to conventional surfactants in the study area for improving oil recovery by reducing oil-water IFT, clay swelling, and swelling-induced migration.