Anatomic and molecular pathology is a branch of pathology that encompasses the study of diseases at both macroscopic and microscopic levels, integrating traditional anatomical pathology with molecular biology techniques. Anatomic pathology composed of histopathology, cytopathology, autopsy pathology. Molecular pathology composed of advanced technologies such as next-generation sequencing and gene expression profiling are often highlighted for their contributions to precise disease characterization. It emphasizes the interdisciplinary nature of the field, showcasing how insights from traditional anatomical pathology are complemented and expanded by molecular analysis. This integration provides a comprehensive understanding of disease processes, paving the way for personalized medicine approaches. Anatomic and molecular pathology significantly influences clinical practice by contributing to accurate diagnosis, prognosis prediction, and selection of targeted therapies.