Fertility preservation is crucial for individuals facing infertility risks due to medical treatments, genetic conditions, or personal choices. Techniques such as sperm and embryo freezing, oocyte vitrification, and ovarian tissue cryopreservation provide viable options. Nurses play a pivotal role through patient education, emotional support, and advocacy, ensuring informed decisions and equitable access. Established methods like sperm cryopreservation are reliable, while advancements in testicular tissue preservation and emerging techniques such as artificial ovaries and gene editing offer promising avenues. Ethical, legal, and psychosocial considerations underscore patient autonomy and support throughout the fertility preservation journey, emphasizing nurses’ critical role in optimizing outcomes and holistic care.