The chapter on Advancing Pharmacotherapy: Integrating New Technologies into Pharmacy Services provides a comprehensive exploration of the transformative role technology plays in reshaping contemporary pharmacy practice. The narrative begins with an insightful overview of the evolving landscape of pharmacy, emphasizing the paradigm shift from traditional medication dispensing to a more comprehensive, patient-centered approach. It delves into the challenges and opportunities pharmacists face in an era marked by an aging population, chronic diseases, and the demand for efficient healthcare services. The subsequent sections meticulously examine the multifaceted impact of technology on pharmacotherapy. From electronic health records and telepharmacy services to precision medicine and artificial intelligence, each technology is scrutinized for its potential to enhance patient outcomes, safety, and overall quality of care. The chapter further elucidates the ethical considerations and challenges associated with the integration of technology, addressing issues of privacy, equity, and responsible AI use in pharmacotherapy. Case studies and success stories exemplify the tangible benefits of technology implementation, showcasing improved medication adherence, patient safety, and streamlined workflows. The narrative concludes with a forward-looking perspective on emerging technologies, anticipating developments such as blockchain, 3D printing and virtual reality. A compelling call to action urges pharmacists to embrace continuous learning, champion interprofessional collaboration, and advocate for ethical technology use. The future of pharmacotherapy, as depicted in this chapter, is undeniably intertwined with the dynamic and rapidly evolving landscape of technological innovation.