Sadabahar or Baramasi (Catharanthus roseus) is a popular household name for its cosmopolitan distribution. It is a perennial subshrub growing mostly in tropical and sub-tropical regions. The plant is a source of various alkaloids of high pharmacological importance. It is highly acclaimed for its anti-diabetic, anti-inflammatory, antibacterial, antifungal properties. Recent studies have established its anticancer properties as well. It is also effective in case of asthma and stomach cramps. The phyto-components of the plant are responsible for wound healing ability. The alkaloids are even used in chemotherapy as anti-cancer drugs. The medicinal properties of sadabahar are miscellaneous ranging from reducing the level of cholesterol in blood, lipid lowering activities, anti-hypertensive ability to highly potential antioxidant capabilities. The pharmacological importance of the plant dates back to centuries old traditions to till date where researches are still carried on to enhance the production of these pharmacological valuable alkaloids in the plant. Cultivation of the plant is easy and economical due to its adaptability nature. Novel strategies like designing nanomaterials derived from the plant parts are seen to exhibit outstanding results for clinical use.