Night jasmine is also known as Cestrum nocturnum is an evergreen shrub that grows in tropical and sub-tropical regions throughout the world. Night blooming jasmine is a popular ornamental plant due to its showy and fragrant white flowers. It is also used as a hedge plant and cultivated as a medicinal plant. The medicinal properties of the queen of the night include Flavones glycoside/ Steroidal saponins/Cytotoxicity: Atrial contractility effect, Antiepileptic/Analgesic, Antibacterial, Antitumor, Mosquito Larvicidal Activity/ Aedes aegypti, Fumigant, Antioxidant/Essential oil, Anti-inflammatory, Anti-diabetic, Pesticide, Antimicrobial Weak Anti- HIV activity, Anti hyperglycemic/Anti hyperlipidemia, Antifungal, Wound healing activity, Anti proliferative and Apoptosis induction, Anticoagulant, Local Anesthetic Effect, Antidepressant, Anticonvulsant, Mosquito repellent activity, Hepatoprotective. The present paper reviews the history, Pharmacological activity, Taxonomical classification, Synonyms, Medicinal and Traditional use, Material Method.