Precision nutrition is a new discipline of research in nutrition. It is also referred to as personalized nutrition. Precision nutrition mainly focuses on individual nutrition rather than a group of people. It works on the concept that there is biological variability among the individuals which results in variations in their responses to different foods. Thus, if the factors responsible for these variations in nutritional status and health of people can be identified, the outcomes can be assessed easily and solutions can also be predicted. Precision nutrition uses personal information to assist individual in improving health condition and also to give nutritional advice. It provides recommendations on the basis of uniqueness of individual such as the genetic background, sex, medical background, lifestyle, cultural belief likes and dislikes etc. It works in a very smart way by providing more specific and target centered approach to resolve the problem related to nutrition and disease. Precision nutrition understands that as we all have unique fingerprints, different bodies and different metabolisms, likewise we all need different nutrients and different ways to treat our diseases. Conceptually, it is very interesting to find out the personal details of an individual and suggesting him accordingly. But this approach to precision nutrition requires collection of lots of different kinds of data which is not easy to assemble and evaluate. This is a time-taking, energy consuming and complex approach. So, here Precision nutrition means integration of complex arrays of factors and utilizes them to provide precise nutritional advice to an individual.