A safe and productive soil exists when its biological, chemical, physical properties, all correlated to each other, contribute to balance all activities occurring in it. Among these properties the activities of soil enzymes play a fundamental role because they mediate numerous chemical reactions involved in soil nutrient cycling, transformation of plant and microbe debris, mineralisation and transformation of organic matter within the carbon cycle, transformation and degradation of potentially hazardous pollutants, thus contributing to the restoration and remediation of polluted soils.