Aloe vera is a characteristic item that is currently a day constantly utilized in the field of cosmetology. In spite of the fact that there are different signs for its utilization, controlled preliminaries are expected to decide its genuine viability. The aloe vera plant, its properties, system of activity and clinical uses are momentarily evaluated in this chapter. Aloe vera has different therapeutic properties like calming, antibacterial, antiviral, and antitumor which speeds up injury mending and helps in treating different injuries in oral depression. Advantages related with Aloe vera have been ascribed to the polysaccharides contained in the gel of the leaves. The leaves of Aloe vera are fleshy, erect, and structure a thick rosette. Numerous utilizations are made of the gel acquired from the plant's leaves (Marshall JM., 1990). Aloe vera has been the subject of much logical investigation in the course of the most recent couple of years, with respect to a few asserted helpful properties. In this chapter, we will take a glance at a portion of these cases and examine the exploration behind them.