Around the world, plant viruses cause serious reductions in marketable crop yield and in some cases we can see plant death. In most cases, the efficacious way to control virus diseases is through genetically controlled resistance. The virus resistance strategies are based on either natural resistance or engineered virus-resistant plants. Recent progression in understanding the molecular mechanisms underlying the roles of resistance genes has promoted the development of new anti-virus strategies. Although, developing virus-resistant (VR) crops through traditional breeding can take many years, and in some cases it is not even possible. Virus diseases are notable threats to modern agriculture and their control remains a challenge to the management of cultivation.