For many years, Synthetic fertilizers has been used in agricultural field. Some of the famous names are Ammonium Nitrate (NH4NO3), Urea, Calcium ammonium nitrate [Ca (NO3) 2.NH4.10H20], Phosphogypsum (CaSO4.2H2O), DDT (Dichlorodiphenyl trichloroethane) and many more. But there were many side effects associated with enormous use of these synthetic fertilizers like it made a negative impact for environment leading to soil and water pollution and it also effected the health of farmers. So, to overcome all of these effects, our researchers started to search for eco-friendly pesticides that can be used without causing any bad impact and thereby they came to a conclusion regarding “Biopesticides”. Biopesticides are the alternative agents that are used for pest management and are developed with the help of living microbes or natural products. Their production is very much economical, eco-friendly and way cheaper than chemical fertilizers. They are very much target specific that is they shows their effect only on target specific plants thereby not effecting the health of the farmer using it. Use of Bacillus thuringiensis as a microbial biopesticides, PIPs, genetically modified plants that itself act as a pesticides etc. catches a limelight of discussion. So, in this review paper we have discussed about different types of R&D based Biopesticides, there production strategies, applications and future prospects associated with this.