Most of the time, vegetative crops or field-grown plants get systematically infected by a variety of pathogens such as fungi, phytoplasma, viruses, and viroids. Viral infections cause significant crop yield losses and have long been a barrier to the sustainable expansion of agricultural output. Viruses cause many important plant diseases and reduce the yield of the plants as well as their nutrition. Field crops such as banana, cassava, potato, sugarcane, fruit crops such as stone, pome and citrus and ornamentals that are normally propagated by vegetative methods are more vulnerable to virus accumulation over several generations. Most plant viruses are spread by vector organisms that forage on the plant's growth ability, which leads to death. So, the eradication of viruses is much needed for the yield of the plants. Fungal and bacterial plant infections may be controlled by the use of fungicides and bactericides. Traditionally, there was a method called thermotherapy that was used to eradicate viruses but was also used to obtain virus-free plants from infected stock plants, which is a cumbersome process. Since 1952, the shoot meristem technique has been widely used for virus eradication.